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Staying Young At Heart: The anti-aging effects of exercise



Number: 00S07. Issue: Spring 2000

Author[s]:
Jennifer Lin and Janice Lin

Keywords:


Abstract:


Are there ways to prevent aging?  Can we rely on ourselves to maintain a long and healthy life? Dr. Ronald Klatz, President of the American Academy of Anti-Aging, believes that the struggle against aging is a multi-faceted process. "There is no one best method to prevent aging," Klatz says. "Anti-aging is early detection, prevention and reversal of aging-related disorders."

            Exercise, whether one is young or old, is a vital factor in maintaining health. Regular physical activity can reduce the chances of contracting diseases typically found in the elderly, such as diabetes, obesity, and high blood pressure. As reported by the American Heart Association, exercise can also prevent osteoporosis and colon cancer. In doing so, exercise prolongs one?s life span and leads to healthier living. "If you prevent cardiovascular disease, you will save seven to thirteen years. If you prevent cancer through exercise, [which] stimulates the immune system, you can pick up another three years. If you prevent diabetes, you can pick up another year and a half. Potentially, if you do all the right things, you can probably expect ten to thirteen years of longer, healthier living," Klatz says.

            As with most things, however, too much exercise can cause harm to the body, often taking the form of tissue breakdown through the formation of free radicals, reactive chemical molecules. "Exercise is a trade-off," Lester Packer, UC Berkeley Professor of Molecular and Cell Biology, says. "There are certainly many beneficial effects of exercising, particularly when one trains. Through physical training, the body adjusts the proteins that it synthesizes and strengthens the antioxidant defense mechanism. These antioxidants are substances or enzyme systems that counteract the toxic effects of free radicals. The body needs free radical reactions to live, but if free radicals are generated at random, they can be toxic and damage all sorts of biological molecules, which would lead to damage of cells and tissues, and can lead to acceleration of aging and to the occurrence of age-related diseases. If you?re not trained in exercise, you can generate free radicals [through exercise] that may be damaging."

            Instead, most physicians and professors agree that an exercise prescription should be made after careful analysis of an individual?s abilities. The intensity of the exercise should target 60 percent of maximum heart rate, approximated by 220 minus the individual?s age. "At any age, the type of physical exercise you undertake should be adjusted to your own lifestyle and what you might be able to train for. I think regular exercise is a good thing," Packer says.

            In developing an exercise program, individuals can tailor one to their needs by including more endurance (aerobic) training or resistance (weight) training. "Weight training is slow and repetitive, stimulating the production of bone, muscle and the neuroendocrine system, which is the complex interaction of the hormones between the brain and the body. Aerobic exercise works primarily on circulation, the heart, and the pulmonary function," Klatz says.

            For maximum results, various types of exercises should be included. "The change that takes place in the human body with exercise is going to be specific to the type of stress you put on it," Joseph Signorile, University of Miami Associate Professor of Exercise Physiology, says. "Each type of exercise carries its own benefits. I believe the best thing is to design an exercise program that can address the needs of the individual in what we call a periodized program. In a periodized program, when we work, we gear that work toward a specific need. After we finish that period of work, we give a recovery period and then we try to address the next need. Everything needs to be addressed as individual entities, and I don?t think you can do that all at once. I think you need to do it in a good cyclic program that addresses each while not allowing you to lose any of them over a long period of time."

 

As one ages, joints lose their flexibility, causing movements to be slower and more painful. Inactivity among the elderly population results in reduced bone density and bone loss, known as osteoporosis, which in turn leads to a higher likelihood of fractures. According to James L. Christiansen and John M. Grzybowski in Biology of Aging, elderly who engage in exercise have bone mass that is 40 percent denser than inactive peers. "For osteoporosis, weight training [is most useful]," Klatz says. "Bones are stimulated by mechanical energy. Weight training delivers mechanical stress to the bone and stimulates the neuroendocrine system to release calcitonin to repair and [build] new bone."

            Loss of muscle mass is another symptom associated with aging, but is more often caused by inactivity rather than by aging. Through exercise, the elderly can gain lean body mass and improve functional mobility. Atrophy, the wasting away of the muscle, causes loss of muscle tone, weakening the skeletal muscle contraction. Another muscular problem frequently encountered by the elderly is cramping due to decreased circulation. "It?s known that people who go up in space and sit around for a long time, highly immobilized in zero gravity (weightlessness), often develop bone defects. They lose bone. In order to keep the bone strong, you need to have physical exercise," Packer says.

            Exercise can also improve maximum oxygen consumption, a measure of how much oxygen one?s body can process, which normally decreases with age; less activity results in less use of muscles that require oxygen. Exercise improves the body?s ability to use oxygen to produce energy.

            With age comes a decreased body size, and thus a decreased heart size. The left ventricle, the chamber which accepts blood from the lungs, decreases while the left atrium, which pumps blood into circulation, increases. In many instances, the veins expand, and, as a result, the valves fail to function. The blood, in turn, is trapped in tiny capillaries that may bulge or rupture. By exercising, the elderly can reduce blood pressure while maintaining the elasticity of blood vessels, lowering the chance of a rupture. "Aerobic exercise reduces high blood pressure," Klatz says. "You want to relax the arteries of the body. Sympathetic nervous tone lowers blood pressure and helps improve circulation. Aerobic exercise tones the heart and the major blood vessels. It also stimulates the growth of new blood vessels, and dilates capillaries. You have hundreds of miles of capillary blood vessels circulating through your body. Many times, they shrink and shut down as we get older; aerobic exercise helps open them up and improve circulation. When you open them up, you reduce pressure. Aerobic exercise reduces the chance of heart attack by 50 percent."

            Studies have also shown that exercise can reduce the chances of getting diabetes mellitus by stabilizing glucose metabolism. "Exercise helps to regulate the insulin-receptor sites on the cells of the body," Klatz says. "Exercise also helps regulate the pancreas? sensitivity to glucose and its release of insulin. Exercise counteracts the endocrine system and is very effective in the prevention of diabetes among the elderly."

            As tissues lose elasticity, pain can occur because an increased pressure or friction is applied to the nerves. Many diseases related to old age result from neurochemical changes that occur in the body. A decreased level of acetylcholine (a neurotransmitter which helps conduct nerve impulses) results in Alzheimer?s disease, norepinephrine deficiency causes disease, and lack of dopamine brings about Parkinson?s disease.

 

By engaging in consistent activity, both youth and elderly can slow the aging process. The greatest benefit of engaging in an exercise program is the increased chance of habitual exercising. For almost everyone, the main challenge lies in continuing the physical activity after it has been started. "Elderly do not exercise for the same reason [younger] people don?t exercise," Klatz says. "It?s an anathema. Exercise is strenuous, time consuming, and uncomfortable. Most people are pleasure-seeking. If they?re not highly motivated, they won?t exercise. It?s not something we?re innately programmed to do; we?re innately programmed to relax and conserve energy, causing obesity. Given the choice, most people will sit around and watch television."

            College students, in the prime of their years, oftentimes forget to exercise to maintain their physical well-being. This short-sightedness can speed up the aging process. "I don?t think that our body should be neglected for years and years," Signorile says. "When we sit down and condemn ourselves to inactivity for hours rather than going out and engaging in physical activity, we?ve already planted the seeds of aging when we?re young. While we may not be able to prevent aging, we may be able to prevent, through lifelong exercise, what we consider the properties of aging ? that is, our ability to remain independent. When everything is said and done, that?s really what we all want. We want to keep our self-respect; we want to keep our independence; we want to know we can take care of ourselves all through our life."

 

REFERENCES:

Ronald Klatz, President of the American Academy of Anti-Aging

Joseph Signorile, University of Miami Associate Professor of Exercise Physiology