Welcome To The Hockemeyer Lab

The focus of our work is to establish reliable models of human diseases using genetically engineered human and stem cell and mouse models and functional genomics screening approaches. We are particularly interested in developing rigorous genetic approaches to study human disease, development and cell biology where conventional animal models or tissue culture systems do not adequately recapitulate human biology. To do this we are  leveraging our expertise in human stem cell techniques and genome editing, humanized mouse models to elucidate processes of  human stem cells renewal and differentiation and during tumor formation.

Recent Publications


iSCORE-PD: an isogenic stem cell collection to research Parkinson’s Disease. Oriol Busquets,  Hanqin Li,  Khaja Mohieddin Syed, Pilar Alvarez Jerez, Jesse Dunnack, Riana Lo Bu,  Yogendra Verma,  Gabriella R. Pangilinan, Annika Martin, Jannes Straub, YuXin Du, Vivien M. Simon,  Steven Poser,  Zipporiah Bush,  Jessica Diaz,  Atehsa Sahagun, Jianpu Gao, Dena G. Hernandez, Kristin S. Levine, Ezgi O. Booth, Helen S.Bateup,  Donald C. Rio,  Dirk Hockemeyer,  Cornelis Blauwendraat, Frank Soldner. bioRxiv 2024.02.12.579917;  doi: https://doi.org/10.1101/2024.02.12.579917. Preprint.

Distinct senescence mechanisms restrain progression of dysplastic nevi. Franziska K Lorbeer, Gabrielle Rieser, Aditya Goel, Meng Wang, Areum Oh, Iwei Yeh, Boris C Bastian, Dirk Hockemeyer, Distinct senescence mechanisms restrain progression of dysplastic nevi, PNAS Nexus, Volume 3, Issue 2, February 2024, pgae041, https://doi.org/10.1093/pnasnexus/pgae041

Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Bredeson JV, Mudd AB, Medina-Ruiz S, Mitros T, Smith OK, Miller KE, Lyons JB, Batra SS, Park J, Berkoff KC, Plott C, Grimwood J, Schmutz J, Aguirre-Figueroa G, Khokha MK, Lane M, Philipp I, Laslo M, Hanken J, Kerdivel G, Buisine N, Sachs LM, Buchholz DR, Kwon T, Smith-Parker H, Gridi-Papp M, Ryan MJ, Denton RD, Malone JH, Wallingford JB, Straight AF, Heald R, Hockemeyer D, Harland RM, Rokhsar DS. Nat Commun. 2024 Jan 17;15(1):579. doi: 10.1038/s41467-023-43012-9. PMID: 38233380

Recent News

2023 Hockemeyer Holiday Party


2023 Hockemeyer Holiday Party

Hockemeyer Holiday Party


Hockemeyer Holiday Party

Hockemeyer Halloween Party


Hockemeyer Halloween Party

2022 Bateup and Hockemeyer Lab Joint Annual BBQ


2022 Bateup and Hockemeyer Lab Joint Annual BBQ

Shy passed his quals


Congratulations to Shy for passing his qualifying exam!

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Li Ka Shing Center


We are currently looking for motivated postdoctoral scholars. Interested applicants should submit their CV and cover letter to:

Inside Li Ka Shing Center


Office phone: (510) 664-9851

Lab phone: (510) 664-4891

Lab e-mail address:

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